Tissue resolved, gene structure refined equine transcriptome

for spatially - resolved transcriptome analysis

It is well known that cells in tissues display a large heterogeneity in gene expression due to differences in cell lineage origin and variation in the local environment at different sites in the tissue, a heterogeneity that is difficult to study by analyzing bulk RNA extracts from tissue. Recently, genome-wide transcriptome analysis technologies have enabled the analysis of this variation with ...

Comparative transcriptome analysis of equine alveolar macrophages

REASONS FOR PERFORMING STUDY Alveolar macrophages (AMs) are the first line of defence against pathogens in the lungs of all mammalian species and thus may constitute appropriate therapeutic target cells in the treatment and prevention of opportunistic airway infections. Therefore, acquiring a better understanding of equine macrophage biology is of paramount importance in addressing this issue i...

Depth-resolved fluorescence spectroscopy reveals layered structure of tissue.

A confocal fluorescence spectroscopy system is instrumented to study depth-resolved autofluorescence in biological tissue. The system provides the capability of optical sectioning with the maximal detectiondepth up to 120 m in the examined tissue samples. It was found that the topmost keratinizing epithelial layer produces strong fluorescence similar to collagen. The fluorescence signal from ep...

Running Title: Gene Discovery and Tissue-specific Transcriptome of Chickpea

The Refined Process Structure Tree

We consider a workflow graph as a model for the control flow of a business process and study the problem of workflow graph parsing, i.e., finding the structure of a workflow graph. More precisely, we want to find a decomposition of a workflow graph into a hierarchy of sub-workflows that are subgraphs with a single entry and a single exit of control. Such a decomposition is the crucial step, for...